Writing inside the autobiography, the Nobel laureate Franзois Jacob described how the procedure of science was actually quite distinct from what was eventually written and published within the peer-reviewed literature. 1 He related how Sydney Brenner to his research and Matthew Meselsen initially had setbacks if they attempted to identify a hypothesized intermediary molecule that took information from genes and allowed protein to be synthesized inside cells. He along with his colleagues attempted, without luck, to exhibit that the factor, which today we realize as mRNA, attached itself to ribosomes, the cell’s protein-manufacturing machinery. So 1 day, discouraged, Jacob said, he and Brenner took some slack and went to a Pacific Ocean beach, where Brenner at some point exclaimed that magnesium was very important to binding.
Once the two gone back to the laboratory, they added enough magnesium to their experiments and then showed the factor associated with ribosomes. Without sufficient magnesium, the mRNA will never attach to ribosomes. The scientists had provided evidence for the existence of mRNA, which we now know transcribes information from DNA into a language that ribosomes can understand. But the paper reporting the results, which appeared in the wild in 1961, had not been a narrative that is historical of happened. The paper that is scientific mRNA’s binding to ribosomes as a function regarding the concentration of magnesium, without reference to the eureka moment in the beach.
Jacob compared the limitations of a scientific publication to capture the “truth” of the scientific process to a snapshot of a horse race. He said that scientific writing transforms and formalizes research and substitutes order when it comes to agitation and disorder that animate life in a laboratory.
Articles are foundational to for academic recognition
Although academic papers may not reflect the “reality” associated with research process, peer-reviewed scholarly and literature that is scientific a key repository for the advancement of society’s knowledge. (more…)